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The neuroprotective effects come through multiple pathways: inhibition of nitric oxide synthesis under ischemic conditions, antioxidant activity, protection against glutamate neurotoxicity, and mitochondrial stabilization under calcium dysregulation

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Studies have also shown its promise in research on inflammatory bowel conditions, including ulcers and Crohns disease

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Hayes, M

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Pediatric acute-onset neuropsychiatric syndrome (PANS) and pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) represent unique cases of infection-triggered brain autoimmunity

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If the 4 mg maintenance arm proves non-inferior for weight maintenance in Phase 3, researchers may be able to titrate up to a high working dose during the active weight-loss phase, then step back down to a lower 4 mg maintenance dose for the long stabilization phase

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Circadian Rhythms 3 , 15 (2005)

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