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Moreover, a few studies have shown that long-term MTX use can lead to lymphoproliferative disorders (LPDs) in both nodal sites and extra nodal sites, such as the skin, lungs, epipharynx, thyroid gland, nasal cavity, spleen, and kidneys, especially for patients who are positive for EBV infection [7073]

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doi: 10.1016/j.oooo.2014.12.019 184 LederleWHartensteinBMeidesAKunzelmannHWerbZAngelPet al

Anti-asthenic (human): A 14-day intranasal course in neurasthenia was well tolerated and reported energy-supporting, anti-asthenic effects [2]

A549 cells treated with acetate showed a significant reduction in IAV replication at 8 h and 24 h post-infection, as evidenced by decreased expression of the viral M1 gene (Figure 8A)