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Studies have consistently reported that inhibiting NNMT activity or downregulating NNMT expression leads to significant increases in NAD + levels in mouse adipocytes (Neelakantan et al., 2018) and hepatocytes (Song et al., 2020)

Initially developed for obesity treatment, AOD9604 showed weight-reducing effects in rodent models comparable to those of full-length GH, but without inducing diabetes or stimulating IGF-1 production

Furthermore, vitamin B12 is important for brain health, as it helps in the production of neurotransmitters that regulate mood and cognitive functions

2000;279(3):E501-E507
