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its overexpression along with C3 complement shows the inflammatory state caused by OS (116)

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The major approaches to overcome CR are synthesizing platinum analogs with fewer side effects and superior activity, improving cisplatin delivery by encapsulating them in NPs to achieve better bioavailability at the tumor site, optimizing concurrent administration of molecularly targeted anticancer agents along with cisplatin that have the ability to combat CR in OC

Advise females of reproductive potential to notify their provider if they were pregnant during therapy with CYANOKIT [see Use In Specific Populations ]
