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10.1016/j.neubiorev.2018.01.010

antibodies contemplated herein will specifically bind cancer cells that express ALPPL2 or a domain thereof that is bound by the M25ADLF, M25ADLFEG, M25ADLFDS, M25FYIA, M25FYIAEG, M25FYIADS, M25, M25EG, M25DS, the antibody binds to cell expressing ALPPL2 with an affinity greater than (K D less than) about 5 nM, or less than about 4 nM, or less than about 3 nM, or about 2 nM or less when measured on live cells by FACS

NAD+ Shot NAD+, or nicotinamide adenine dinucleotide, is a coenzyme found in all living cells

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A., Abu-Remaileh, M., Wolfson, R