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Additionally, there are drug efflux pumps such as p -glycoprotein (P-gp), multidrug resistance associated protein (MRP) and drug metabolic enzymes, at the BBB to remove and/or inactivate small drug molecules from the brain [1]

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As mitochondria are the primary source of ROS, their function could be compromised by excessive antioxidants

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There was also an apparent impact of the ACore alone to increase spine density and the PSD count