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Treatment with P38 inhibitors reduced cytokine enhancer-binding polypeptide (CEBP-) phosphorylation in vivo and correspondingly reduced PPAR phosphorylated expression

The differences in the metabolism of these ACs may potentially become important biomarkers for distinguishing depression and schizophrenia, but these possibilities are yet to be explored in further research (Table 5)

Blood analysis for L-carnitine derivatives showed that glutaryl carnitine and carnosyl carnitine were significantly decreased in ASD group and the authors of this publication suggested that those 2 compounds may be potential biomarkers for diagnosis of ASD

Female APOE4 mice showed an upregulation in the mitochondrial dysfunction pathway but a down regulation in mitochondrial protein import, complex III assembly, TCA cycle, and glyoxylate metabolism and glycine degradation pathways ( Figure 2C )