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Data Animal Data Reproduction studies have been performed following administration of acetylcysteine during the period of organogenesis in rats at oral doses up to 2000 mg/kg/day (1.1 times the recommended total human intravenous dose of 300 mg/kg based on body surface area comparison) and in rabbits at oral doses up to 1000 mg/kg/day (1.1 times the recommended total human intravenous dose of 300 mg/kg based on body surface area comparison)

doi: 10.1016/j.biopha.2019.109732 42 FoLMotaSIRegoAC

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"Cutting down on caffeine and not drinking liquids after dinner may help with the constant need to urinate, especially during the night," says Dr