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In patients with diabetic retinopathy, abnormal carnitine metabolism may exacerbate oxidative stress and inflammation in the retina and promote the development of the disease [317]
In human HCC cell lines, knockdown of HMGCS2 increases tumor growth and cell migration, while HMGCS2 overexpression decreases cell proliferation and increases apoptosis (Wang et al., 2019b
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doi:10.3390/nu13124562 [14] Picard M, McEwen BS
