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Although the mechanism(s) underlying NASH progression remain to be fully elucidated, accumulating evidence suggests that both oxidative stress and the pro-inflammatory cytokine tumor necrosis factor- (TNF) are critical contributors in this process 5

Growth Hormone & IGF Research (1999) 10

Genotoxic pesticides induce DNA damage, mutations, and chromosomal instability, while oxidative stress arising from excessive reactive oxygen species can cause lipid peroxidation and DNA strand breaks [224,225]

AOD-9604 Peptide is commonly investigated in laboratory models examining adipose tissue metabolism, lipid oxidation mechanisms, and metabolic regulation processes

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Indole derivatives play a crucial role in the inflammatory response of colon tissue in UC and CD through the aryl hydrocarbon receptor (AhR) pathway [113]