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13 M Dihexa and 2.5 ng/ml HGF or 10 13 M Nle1-AngIV and 2.5 ng/ml of HGF produced a near ceiling effect, similar to biological responsive doses of each ligand alone ( To further strengthen this perceived commonality of mechanism, the novel HGF antagonist Hinge was employed and evaluated for its effects on hippocampal neurons stimulated with AngIV analogues and HGF

Se-catalysed standard reaction conditions N -phenoxyamides ( 1 ) (0.20 mmol), PhSeBr (10 mol%), were weighed into a 10 mL tube, to which was added 1,4-dioxane (2.0 mL)

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(Nature Communications) demonstrated that selective NNMT inhibition in diet-induced obese mice produced significant reductions in fat mass and improvements in insulin sensitivity without caloric restriction