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10.1097/FJC.0b013e3182239eb7 297 YamaguchiT.SanoK.TakakuraK.SaitoI.ShinoharaY.AsanoT.et al (1998)

[DOI] [PubMed] [Google Scholar] 281.Yuan S., Li H., Yang C., Xie W., Wang Y., Zhang J., Cai Z., Mao Z., Xie W., L T

At 4 mg, the relative risk of diarrhea was 1.64 compared to placebo, with a 95% confidence interval of 0.77 to 3.49
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In another study with pubertal gynecomastia, no significant difference was demonstrated between the anastrozole and placebo groups in patients suffering from pubertal gynecomastia (77)

Although preclinical studies on BSPs have not reported significant toxicity, formal, comparative safety, and toxicology studies are necessary to fully characterize their profile relative to established agents such as beta-glucan
