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Variations in oral physiological pigmentation are genetically determined unless associated with some underlying disease.In this article, we discuss some aspects of the biophysiology of oral melanocytes, of the functions of melanin, and of physiological oral pigmentation.

Unregulated nasal tanning sprays, often containing Melanotan II, are gaining popularity on social media but they pose serious health risks: These sprays may contain a synthetic hormone that stimulates melanin and enhances tanning effects

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