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We show that these phenotypes can be rescued by downregulating the OCT-1 paralogue, OCT-2
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seabream broodstock, maintaining an equal sex ratio (three males and three females)
Furthermore, 16S rRNA sequencing revealed a rebalancing of the gut microbiota, characterized by a reduced Firmicutes/Bacteroidota ratio, enrichment of beneficial taxa like Bacteroidota and Alloprevotella, suppression of pathobionts such as Desulfovibrionales, and partial restoration of microbial diversity
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