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[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Sansone A., Romanelli F., Gianfrilli D., Lenzi A

In: Brent J., Burkhart K., Dargan P., Hatten B., Megarbane B., Palmer R., White J., editors

373 A novel glutaminase inhibitor, BIX01294, suppresses pancreatic cancer by inhibiting KDM6B-mediated glutaminase expression, thereby disrupting redox balance

After prehybridization, HIF-1 and 18S rRNA probes were hybridized in prepared hybridization buffer in NCM460 cells

It is a major source for methyl groups via its metabolite trimethylglycine (betaine) that participates in the S-adenosylmethionine synthesis pathways
