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ALD is intricately intertwined with stress mechanisms such as oxidative stress mediated by reactive oxygen species, endoplasmic reticulum stress, and alcohol-induced gut dysbiosis, culminating in increased inflammation

Mitochondrial dysfunction is implicated in atherosclerosis development and progression [136]

The glutamine residue (Q89 in the Clathrin box, Q155 in the W-box and Q195 in the Arrestin box) behaves as an anchoring residue forming a hydrogen bond with the peptides backbone (Fig

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alternatively, R 4a and R 4b , or, R 4a and R 5a , or, R 4a and R 8a form the ring B together with the carbon to which they are bonded

It has also been noted that different time intervals are employed for the radical scavenging process to mature (Scherer et al