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First, however, it's important to keep in mind the axiom, 'If a little is good, a lot is not necessarily better.' Even basic substances required for life can be overdosed or underdosed, contributing to harmful life-threatening consequences

Cardiovasc Res 73:120129 Wyke SM, Tisdale MJ (2005) NF-B mediates proteolysis-inducing factor induced protein degradation and expression of the ubiquitin-proteasome system in skeletal muscle

Mintl et al., 2022

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it is usually explained with a more pronounced immunogenic character of a highly iodinated thyroglobulin [53]

Chen PH, Chen WC, Hou MC, Liu TT, Chang CJ, Liao WC, et al