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BPC-157's ability to balance NO signaling in preclinical models positions it as a dual-action candidate: reducing reflux frequency while simultaneously accelerating tissue repair

However, BPC-157 is not approved for human use by any regulatory agency, and its safety remains largely unproven

There were inhibited mRNA of inflammatory mediators (iNOS, IL-6, IFN and TNF-), increased expression of HSP 70 and 90, and antioxidant proteins, such as HO-1, NQO-1, glutathione reductase, glutathione peroxidase 2 and GST-pi [30]

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