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Impairment of several immune functions and redox state in blood cells of Alzheimer's disease patients
Age was categorized into 4 groups (30 years and younger, 3150 years old, 5169 years old, and 70 years and older)
Hydroxytyrosol (HT) increased antioxidant capacity and alleviated oxidative stress through the Nrf2 signaling pathway
doi: 10.1073/pnas.0506084102 9 YanHHNMrukDDLeeWMChengCY
These ROS trigger the activation of pro-inflammatory transcription factors, namely NFB and activating protein-1(AP-1), resulting in enhanced inflammatory cytokines/chemokines expression
The seven faces of SIRT7
