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Addressing the challenge of overcoming or preventing inherent or acquired resistance to ROS-based anti-cancer approaches could be a significant concern in the future
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It is conceivable that when GCL is induced tremendously, the step catalyzed by GS may become limiting
Grubb, A
T.CookeJ
The immunomodulatory activity is mediated via multiple pathways, including the promotion of anti-inflammatory cytokine secretion (e.g., IL-10) and the inhibition of pro-inflammatory enzymes [e.g., cyclooxygenase-2 (COX-2)]
