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References Egan K, FitzGerald GA (2006): Eicosanoids and the vascular endothelium

Malonic acid can inhibit the SDH enzyme in the cells' energy engine and is also tied to fat metabolism, with two important areas of relevance

[DOI] [PMC free article] [PubMed] [Google Scholar] 150.Luo F., Sandhu A.F., Rungratanawanich W., Williams G.E., Akbar M., Zhou S., Song B., Wang X

Extracellular matrix remodeling in vascular disease: defining its regulators and pathological influence

Understanding your genetic predispositions in collagen-metabolism and growth-factor pathways can provide additional context

The clinical picture is the most important factor in assessing the significance of results of blood tests assessing cobalamin (B 12 ) status because there is no gold standard test to define deficiency Neurological symptoms resulting from B 12 deficiency may take several months or even years to resolve completely Measuring serum biomarkers such as B 12 or methylmalonic acid is neither helpful nor indicated in assessing or monitoring clinical improvement, neither is titration of injection frequency based on biomarker assessment Self-administration of intramuscular B 12 injections can lead to greater patient satisfaction and better health outcomes What is vitamin B 12