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Liver Int 2017;37:173-178

"G6PD glucose-6-phosphate dehydrogenase [ Homo sapiens (human) ]"

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Glycine 1228 is the sole residue responsible for the stimulation of GSH transport and associated collateral sensitivity in TM16-TM17 To characterize the effect of the original replacement within the nine identified clusters of chimera M8, we first verified that all the mutants were well expressed and addressed to the plasma membrane (Supplementary Fig

Accordingly, our in vitro results showed no rescue effect pertaining to Z-VAD-FMK (a pan-caspase inhibitor) or Nec-1 (a necroptosis inhibitor) in erastin-mediated cellular destruction, whereas Fer-1 (a free radical scavenger) and bicyclol exhibit obvious rescue impact

(iii) hypertension, diabetes mellitus, hyperthyroidism, hypothyroidism, autoimmune diseases, or other endocrine and metabolic disorders