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Development of skin-on-a-chip platforms for different utilizations: Factors to be considered

10.1093/ije/dyt282 [DOI] [PMC free article] [PubMed] [Google Scholar] 10

Hypoxia is able to regulate glycolysis, glycogen synthesis, lipid metabolism and oxidative phosphorylation, thus playing a vital role in tumor cell survival and growth during all stages of metastasis (247)

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J Hypertens 1997
The exception might be intravenous therapies like the MSC case, but even that was experimental