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The current state of hormonal therapy for prostate cancer

The -adrenergic receptor (-AR) agonist ISO has been shown to increase the levels of MCU and MCU complexes in cardiac mitochondria, thereby increasing mitochondrial Ca 2+ concentrations both in vivo and in vitro, preventing cell death, limiting cardiac hypertrophy, and preserving cardiac function during chronic stress [249]

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The acetyl-CoA build up from pyruvate, fatty acids amino acids metabolism becomes a limiting step since free mitochondrial CoA levels decline

Vairachilai S, Anuhya D, Tirkey A, Raja SP (2024) SLBSMOTE logistic blending hybrid machine learning model for chronic polycystic ovary syndrome prediction with correlated feature selection

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