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Numerous clinical studies have shown that regular physical exercise can significantly improve insulin sensitivity by promoting the translocation of glucose transporter proteins to the cell membrane in skeletal muscle cells, thus enhancing glucose uptake and utilization in peripheral tissues (Liu et al., 2023)

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doi: 10.1517/17425247.3.6.643

doi: 10.1038/nrd4432

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Researchers have long been curious about this and have tried to determine what constitutes effective darkness for the circadian clock in several model systems 52,69,70,71