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Expert Review of Vaccines (2014) 2020-2025 Dietary Guidelines for Americans, U.S

Treatment with the probiotics Clostridium butyricum and Bifidobacterium infantis seems to be promising as an adjuvant therapy for the management of the mild hepatic encephalopathy ( According to a meta-analysis of 21 trials, when compared to placebo/no treatment, probiotics seem to be beneficial in treatment of hepatic encephalopathy but do not seem superior compared to lactulose ( Other than the treatment of hepatic encephalopathy, probiotics have also been studied as prophylaxis to prevent recurrence with beneficial effects ( Based on the fact that changes in gut microbiota are inducing liver diseases, an increasing interest in regulating the gut microbiota by probiotics for the treatment of liver disorders is reported ( It is necessary to proceed to high-quality randomized clinical trials with standardized procedures on the undertaken probiotic therapy with appropriate strains and diligent choice of the population size and characteristics in order to get knowledge on the efficacy and safety of probiotics

Data are presented as mean SD or median with interquartile range

Ermund et al., 2018

N-acetyl cysteine in prevention of amphotericin- induced electrolytes imbalances: a randomized, double-blinded, placebo-controlled, clinical trial

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