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Additional investigation is required into the various metabolic products generated by the gut microbiota following the microbial degradation of -lipoic acid and its related analogs because these products, which were confirmed by LCMS/MS chromatography, may be a significant factor in the toxicity of various organs
As seen in the cases discussed, it is not always easy to say which analgesic to start with, and these cases can involve a degree of trial and error
Recent studies have highlighted the protective role of AX on skeletal muscle subjected to metabolic stress induced by high-fat diets (HFD) or accumulation of fatty acids such as palmitate
doi:10.1002/edm2.47 Simon SL, McWhirter L, Diniz Behn C, et al
Alcohol Clin Exp Res 32:573579
