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This increase was associated with enhanced trimethylation of histone H3 at lysine 4 (H3K4me3) at the CCR2 promoter in the NAc ( in vivo , the long-term effects, and the possible side effects

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Although both toxins function via the same mechanism, TcdB is more sensitive to autoproteolytic cleavage induced by InsP6 compared to TcdA [43]

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