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Inhibition of the action of the GTPase involved in mitochondrial fission dynamin-related protein 1 (DRP1) and reduced levels of mitochondrial metabolic proteins lead to many neurodegenerative diseases through the accumulation of misfolded TAU proteins called tauopathies. Normally, TAU is responsible for microtubule attachment and cytoskeleton stability in the brain (Petrozziello et al., 2022)

Affiliation: Department of Neurology, Shandong University Qilu Hospital, Jinan 250012, Shandong, China ORCID: Affiliation: Department of Neurology, Shandong University Qilu Hospital, Jinan 250012, Shandong, China Affiliation: Department of Neurology, Shandong University Qilu Hospital, Jinan 250012, Shandong, China Affiliation: Department of Neurology, Shandong University Qilu Hospital, Jinan 250012, Shandong, China Email: [email protected] ORCID: Explor Neuroprot Ther

Next, we determined the effect of erastin on cellular NO, ROS and lipid-ROS accumulation in BRL-3A cells

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Rutherford (2020) Case report of improved tremor and motor control in a Parkinsons patient after NAD infusions