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[DOI] [PMC free article] [PubMed] [Google Scholar] 26.Zimmerman M, Morgan TA, Stanton K

A further optimization, based on a compromise between metabolic competence and cellular fitness, may provide higher metabolic activity and more stable background TI values

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revealed that GPX4 overexpression prevents basophilic leukemia cells in mice from death caused by oxidative damage (Imai et al., 1996), thus, theoretically, GPX4 overexpression could make cells resistant to oxidative stress-induced ferroptosis