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Research indicates that the introduction of epoxy groups primarily inhibits apoptosis by stabilizing mitochondrial function, while functional groups such as carboxyl, carbonyl, or hydroxyl groups act as secondary pharmacophores, significantly enhancing free radical scavenging efficiency through electron delocalization effects ( The protective effect of rhodioloside, the primary component of Rhodiola crenulata (Hook

Alterations in DNA methylation patterns can influence gene expression and cellular processes within the cardiovascular and neurological systems, contributing to the pathogenesis and progression of these diseases (21, 22)

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