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In current clinical trials, patients are recommended to use HCQ at a dosage of 5 mg/kg body weight or less in order to minimize the risk of retinal complications, even during pregnancy and breastfeeding (99)

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[DOI] [PubMed] [Google Scholar] [217].Yang KY, Mun JH, Park KD, Kim MJ, Ju JS, Kim ST, Bae YC, Ahn DK, Blockade of spinal glutamate recycling produces paradoxical antinociception in rats with orofacial inflammatory pain, Prog

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Nrf2 is the main regulator of the cellular REDOX state and detoxification

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PMID: 169 LiLChenBZhuRLiRTianYLiuCet al

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