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It is important not to self-treat with high-dose B12 supplements before seeing your GP if you suspect deficiency, as this can interfere with diagnostic blood tests and potentially mask underlying conditions such as pernicious anaemia

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[DOI] [PubMed] [Google Scholar] 52.Lim S.C., Tan H.H., Goh S.K., Subramaniam T., Sum C.F., Tan I.K., Lee B.L., Ong C.N

Thats true of other supplements as well, which is why some practitioners recommend taking periodic breaks from supplements