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The ability of CB1 antagonists such as rimonabant to reduce the rewarding properties of several drugs of abuse and inhibit reinstatement of drug seeking following abstinence led to the idea that CB1 receptor blockade could be a viable therapeutic approach for treating drug use disorders (reviewed in Justinova et al., 2009)

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tGSH, total reduced glutathione

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In certain cases, urine tests may also be used to assess methylmalonic acid (MMA) levels, which indicate B12 deficiency

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The reaction rate is influenced by the nucleophilicity of the thiolate, resulting in the enhanced capacity of NAC for reducing disulfide bonds compared to cysteine and GSH (Noszl et al., 2000)

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