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Copper imbalance not only heightens oxidative stress but may also interfere with lipid metabolism and signaling, further advancing the neurodegenerative processes in ALS (111)

Despite their effectiveness, they face limitations such as high costs, complex data interpretation, sensitivity and specificity issues, limited spatial resolution, and restricted coverage to known CpG sites, offering limited insights into the underlying mechanisms of methylation (57)

Shetty A, Cortes JE, Ravandi F, Kadia TM, Garcia-Manero G, Pemmaraju N, Pierce S, Kantarjian HM, Borthakur G

Membranes were incubated overnight with the following antibodies: mouse anti-ADP-ribosylation factor 6 (ARF6

[DOI] [PMC free article] [PubMed] [Google Scholar] Gul B, Sana M, Saleem Aet al

The experimental schedules are shown in Figure 1