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Manifestations of intestinal damage in HS When the core body temperature rises above 42 C, both baboons and mice can exhibit a large loss of intestinal epithelium, and severe damage occurs in both the small intestine and the large intestine, manifested as villous stroma broadening, focal necrosis, edema, and congestion

Clinical box Pyruvate kinase deficiency A child presented with jaundice and abdominal tenderness, which developed following a severe cold

PSPH gene expression analysis was generated in the GEPIA platform comparing GBM tumor samples with TCGA normal and GTEx data

651 The Keap1-Nrf2 pathway has been described as the primary protective response to oxidative and electrophilic stress 652 and is often disrupted in oncogenic process

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43 , 44 SLC38A3 and SLC38A5 belong to system N transporters, which are bidirectional electroneutral glutamine transporters