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Omalizumab Omalizumab, an anti-IgE monoclonal antibody, reduces the expression of high-affinity IgE receptors (FcRI) on basophils, mast cells, and dendritic cells, thereby inhibiting the IgE-mediated signaling cascade (Benito-Villalvilla et al

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[DOI] [PubMed] [Google Scholar] Rottenberg DA, Sidtis JJ, Strother SC, Schaper KA, Anderson JR, Nelson MJ, Price RW (1996) Abnormal cerebral glucose metabolism in HIV-1 seropositive subjects with and without dementia