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The net result is the tendency to increase body weight

DSF/Cu has also demonstrated significant clinical potential in the treatment of NPC: it can induce ferroptosis in tumor cells through the ROS/MAPK-p53 pathway and promote apoptosis and necrosis of -SMA-positive cancer-associated fibroblasts (CAFs)

In addition, inhibition of SLC7A11, genetically or pharmacologically, has been shown to result in cellular defects typically associated with oncogenic pathway inactivation, including suppression of cell proliferation/growth and invasion, defective clonogenic survival, and decreased anchorage-independent growth, whereas SLC7A11 overexpression can exert the opposite cellular effects (Ishimoto et al., 2011

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Structurally, SARS-CoV-2 is a spherical virus covered by a lipid envelope