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Massafra, C

Research suggests that arsenic trioxide, used in the treatment of acute promyelocytic leukemia, induces apoptosis and generates reactive oxygen species (ROS) as part of its mechanism of action (Murillo et al., 2022
HeLa cells were treated with a series of concentrations of buthionine sulfoximine (BSO) for 72 h, a specific inhibitor for the enzyme required in the first step of GSH synthesis (Fig

Recent research in this area in the authors' laboratories was partly funded by the ANR-Genoplante project Redoxome (Orsay), ANR project Vulnoz (Orsay), and the EU Marie-Curie ITN COSI project (Orsay, Leeds)

PubMed Central (PMC)
