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Elevated expression of the PKM2 isoform has been correlated, in numerous cancers, to a hypomethylated state in intron 1 of the PKM gene

doi: 10.1021/ed030p274 10 BroadR

Autophagy 18 , 254282 (2022)
Texture:Lotion

Mater Adv (2021) 2(6):182171

ICLs are the most toxic DNA lesions caused by cisplatin, due to severe distortions in the DNA double helix that blocks replication and transcription, and, as a consequence, inducing cell death 4
