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To optimize the bioavailability of systemically targeted inhaled drugs with favourable aerodynamic properties, dry powder aerosols have been engineered as large porous particles, thereby simplifying inhaler design 103,104,105

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(2) the receptorligand complex undergoes vesicular endocytosis, protecting the cargo from degradation and facilitating intracellular transport

Revised therapeutic window for vancomycin in pediatric patients: evidence from a retrospective therapeutic drug monitoring study

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