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[DOI] [PubMed] [Google Scholar] 20.Tafti M, Petit B, Chollet D, Neidhart E, De Bilbao F, Kiss JZ, et al

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Ligand-activated PPAR can inhibit NF-B signaling by impeding p65 nuclear translocation and reducing p65/PPAR complex formation (81)

Effect of Combinations of ALA and Other Compounds on Female Pathologies: Clinical Studies A recent systematic review investigated the potential benefits of ALA in women with polycystic ovary syndrome (PCOS) and confirmed the improvement of different cardiometabolic factors (such as fasting blood sugarFBS and HOMA-IR) as well as hormonal parameters [148]

225 Inflammatory markers: Neutrophil-to-lymphocyte ratio (NLR) and IL-1 receptor antagonist (IL-1RA) levels correlate with DPN severity, indicating the role of inflammation

Its ability to enhance mitochondrial fat oxidation is particularly beneficial for targeting abdominal fat, a common challenge for women with PCOS