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Clin Gastroenterol Hepatol 2014

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Studies have reported how an AN extract causes damage to the epithelial cells and exhibits a significant toxic effect on keratinocyte proliferation and induces cell death in a dose-dependent manner (Jeng et al., 2003)

The subsequent enzymatic reactions, including intradiol ring cleavage dioxygenation, result in the production of phthalate

DOI: 10.1210/me.2005-0046 Pavri, R., Lewis, B., Kim, T.K., Dilworth, F.J., Erdjument-Bromage, H., Tempst, P., de Murcia, G., Evans, R., Chambon, P., Reinberg, D

JAMA Dermatol 150(1):4750