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Its most consistently reported mechanism

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Furthermore, studies have reported an aberrant activation of NRF2, a key antioxidant transcription factor involved in the regulation of critical antioxidants including glutathione, SOD, and CAT, leading to reduced antioxidant capacity (Hirayama et al., 2020)
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The significance of this study lies less in cartilage regrowth itself than in the conceptual shift it introduces

Kuzniak and Skodowska, 2005)
