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Description
Exp Hematol 9(9):887-92, 1981

While the direct relevance to depression may seem tangential, chronic depression accelerates cellular aging through telomere shortening

Conflict of interests The authors declare that there is no conflict of interest in this paper

If he removed them, it would be unsafe

If abnormalities such as Ras-related in brain GTPases (Rab) inactivation, Soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) dysfunction, or insufficient lysosomal enzyme activity occur during this process, it will hinder the formation of autolysosomes or reduce degradation efficiency, thereby triggering cellular homeostasis imbalance, which manifests as cellular senescence, apoptosis, or inflammatory responses and is closely associated with the occurrence and development of T2DM [80]

Abdominal bloating decreases (partly from visceral fat reduction, partly from reduced inflammation in adipose tissue)
