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PMCID: PMC8443390

Betaine homocysteine methyltransferase (BHMT) uses betaine as a methyl donor to convert homocysteine to methionine in one-carbon metabolism ( Figure 4 )

Stability and storage Extremely easy to absorb moisture, can withstand 200 C above the high temperature and has a good water-soluble and absorbent, easily soluble in water, ethanol, formic acid, almost insoluble in acetone, ether

However, the main concern for topical therapies is whether adequate drug concentrations could be accomplished at the targeted site ( In recent years, electromotive drug administration (EMDA) as a new delivery approach was developed to increase the concentration of drugs into specific tissues ( Potential Novel Drugs of PD As mentioned above, the phenotype transformation of fibroblast to myofibroblast in tunica albuginea has an important role in the pathogenesis of PD
