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It is important that patients tell the care team if they are sexually active, pregnant, or breastfeeding

In addition to the drugs with newly found cardioprotective functions and potential targets supported by clinical trials mentioned above, there are still some natural compounds found in plants or food that have been investigated as potential mitophagy regulators for protecting the heart

Specifically, MALAT1 enhances ULK1-mediated mitophagy in the mitochondria of CMs (Guo et al., 2019)

D., Noakes, M., Clifton, P