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This might be one of the best arguments as to why there needs to be more human trials

[DOI] [PubMed] [Google Scholar] 45.Tehrani-Bagha A.R., Singh R.G., Holmberg K

Sustained activity of DRP1 causes macrophages to exhibit proinflammatory activity even in the absence of LPS, whereas loss or inhibition of DRP1 attenuates M1 polarization

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The IL-17-mediated liver inflammation and fibrosis are noted as being similar to those in PSC

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