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Citation: Phillips, A., & Clements, J

The implication of GST polymorphisms may be significant as studies suggest that that loss of mu, pi and theta GST genes increase susceptibility to inflammatory diseases, and a genetic deficiency of GSTM1 is associated with increased susceptibility to ozone-related asthma [61] and to susceptibility to AFB1-mediated damage to human liver cells [62]

A 2025 systematic review confirmed that probiotic supplementation in T2DM patients leads to a significant elevation in total antioxidant capacity (TAC) and a reduction in malondialdehyde (MDA), a marker of lipid peroxidation (442, 443)

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They achieve this by modifying the biophysical properties of neuronal and glial cell membranes, suppressing pro-inflammatory mediators, fostering the resolution of inflammation, enhancing mitochondrial stability, and reducing reactive oxygen species (ROS) production ( Regarding the potential short-term and long-term side effects associated with high-dose omega-3 supplementation, concerns about bleeding risks have been meticulously evaluated