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They appear to be more likely in younger patients, but it's otherwise impossible to predict who will experience them

10.3109/10408441003610571 32 Fallahi-SichaniM.SchallerM

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Iron chelators, such as DFP, DFX, and DFO, have been shown to significantly reduce iron overload and serum iron levels in patients with thalassaemia [113,114,115]

It is also thought to act as a biological feedback signal following injury while offering strong antioxidant effects by countering free-radical damage

The occurrence of these complications suggests a potential role of immune checkpoint molecules in maintaining cardiovascular homeostasis, and disruption of physiological immune checkpoint signalling might thus lead to cardiac pathologies, including heart failure